Transdermal patches are defined as
pharmaceutical preparations containing active substance. They are available in
varying sizes and intended to deliver the active ingredient through skin.
These patches have been proven to be effective especially for cardiac and hormonal
disorders. The traditional oral dosage forms have considerable setbacks owing
to their reduced bioavailability due to hepatic metabolism. A transdermal
patch comprises of an outer covering which is impermeable to water. The inner
covering consists of a sheet which contains the active substance and generally
impermeable to water, it is designed to support and protect the active
substance.
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These transdermal patches work on
the mechanism of diffusion. The drug diffuses from drug delivery reservoir
through controlled mechanisms such as rate controlling membrane or directly
into the skin. The matrix of active substance may contain a pressure-sensitive
adhesive which ensures adhesion of the skin preparation. The prime advantages
of dermal patches includes they do not have to surpass the gastrointestinal
system and are helpful for GI disorders such as nausea and vomiting. Dermal
patches helps in reduction of drug interactions which are administered orally.
In addition they can substitute oral medications in severe gastric conditions
such as diarrhea and vomiting. They are non-invasive in nature and reduce the
inconvenience caused due to intravenous or parenteral therapies. Recently U.S.
FDA approved sumatriptan iontophoretic transdermal system (Zecuity, NuPathe
Inc) for acute treatment of migraine.
However skin’s non permeability to
wide number of active substance limits the growth of this market. Only certain
relatively potent drugs are suitable candidates for transdermal patches.
Moreover, few patients develop contact dermatitis at the site of application
of these patches, arise the need to discontinue its use. Some of the major
players in this market include Mylan Pharmaceuticals Inc, 3M Pharmaceuticals,
Teva, Access Pharmaceuticals Inc, Accrux Ltd and others.
This research report analyzes this
market depending on its market segments, major geographies, and current market
trends. Geographies analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
This report provides comprehensive
analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for
upcoming years
This report is a complete study of
current trends in the market, industry growth drivers, and restraints. It
provides market projections for the coming years. It includes analysis of
recent developments in technology, Porter’s five force model analysis and
detailed profiles of top industry players. The report also includes a review of
micro and macro factors essential for the existing market players and new
entrants along with detailed value chain analysis.
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